{"id":3367,"date":"2024-12-03T14:16:30","date_gmt":"2024-12-03T13:16:30","guid":{"rendered":"https:\/\/www.curaleafeducation.it\/medical-cannabis\/cannabinoids-thc-and-cbd\/"},"modified":"2025-01-24T10:49:26","modified_gmt":"2025-01-24T09:49:26","slug":"the-endocannabinoid-system","status":"publish","type":"page","link":"https:\/\/www.curaleafeducation.it\/en-uk\/medical-cannabis-in-the-uk\/the-endocannabinoid-system\/","title":{"rendered":"The Endocannabinoid System"},"content":{"rendered":"[vc_row type=”full_width_background” full_screen_row_position=”middle” column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” bg_color=”#454156″ bg_image=”238″ bg_position=”center center” background_image_loading=”default” bg_repeat=”no-repeat” scene_position=”center” top_padding=”5%” bottom_padding=”5%” text_color=”light” text_align=”left” row_border_radius=”none” row_border_radius_applies=”bg” overflow=”visible” id=”intro” row_name=”Intro” enable_gradient=”true” color_overlay=”#0a0a0a” color_overlay_2=”rgba(102,102,102,0.74)” overlay_strength=”0.3″ gradient_direction=”left_b_to_right_t” shape_divider_position=”bottom” bg_image_animation=”none” gradient_type=”default” shape_type=””][vc_column column_padding=”padding-6-percent” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” centered_text=”true” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” column_position=”default” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][vc_row_inner column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” text_align=”left” row_position=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” pointer_events=”all”][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” animation_type=”default” enable_animation=”true” animation=”fade-in-from-bottom” animation_easing=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][vc_custom_heading text=”The Endocannabinoid System” font_container=”tag:h1|font_size:63|text_align:center|color:%23ffffff|line_height:76px” use_theme_fonts=”yes”][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row type=”in_container” full_screen_row_position=”middle” column_margin=”default” equal_height=”yes” content_placement=”middle” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” scene_position=”center” top_padding=”5%” constrain_group_1=”yes” bottom_padding=”5%” top_padding_phone=”20″ constrain_group_5=”yes” bottom_padding_phone=”20″ text_color=”dark” text_align=”left” row_border_radius=”none” row_border_radius_applies=”bg” overflow=”visible” overlay_strength=”0.3″ gradient_direction=”left_to_right” shape_divider_position=”bottom” bg_image_animation=”none” shape_type=”” gradient_type=”default”][vc_column column_padding=”padding-10-percent” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” translate_y=”20px” translate_y_tablet=”30px” translate_x_tablet=”0px” translate_x_phone=”nonw” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color=”#e8edeb” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”20px” column_link_target=”_self” column_position=”default” gradient_direction=”left_t_to_right_b” overlay_strength=”1″ width=”9\/12″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid” column_padding_type=”default” gradient_type=”default”][vc_row_inner column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” translate_x=”-15%” translate_x_tablet=”0%” translate_x_phone=”0%” text_align=”left” row_position=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” pointer_events=”all”][vc_column_inner left_padding_desktop=”20″ column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid” column_padding_type=”advanced” gradient_type=”default”][split_line_heading animation_type=”default” text_direction=”default”]Cannabinoids are compounds that are able to interact with the receptors found in the body\u2019s endocannabinoid system (ECS)<\/strong>. The ECS is made up of numerous receptors, cannabinoids and enzymes. The most well studied receptors are known as cannabinoid receptor 1 (CB1)<\/strong> and cannabinoid receptor 2 (CB2)<\/strong>. CB1 is predominantly found in the brain and is acted upon by the body\u2019s own cannabinoids (endocannabinoids) to regulate emotions, motor coordination and cognition. CB2 is predominantly found in immune cells and activation by endocannabinoids is thought to effect the immune system.\u00a0<\/span><\/p>\n

 <\/p>\n

There are over 120 cannabinoids<\/strong> found in the Cannabis plant, the most common being THC<\/strong> and CBD<\/strong>. THC is similar to the endocannabinoids, by having stimulating effects at the CB1 and CB2 receptors. At sufficient doses THC can overstimulate CB1 receptors<\/strong> in the brain resulting in the \u2018high\u2019 typically associated with its recreational use. At low doses however, this is not typically experienced.\u00a0<\/span><\/p>\n

 <\/p>\n

CBD on the other hand has a diverse role in the ECS. CBD\u2019s main role<\/strong> is thought to be not through direct action at CB1 or CB2 receptors but by inhibiting an enzyme<\/strong> called fatty acid amide hydrolase (FAAH)<\/strong>. This enzyme breaks down the body\u2019s main endocannabinoids. By stopping this enzyme from working as it otherwise would it increases the amount of endocannabinoids available to stimulate cannabinoid receptors. However, CBD also works to change the shape of cannabinoid receptors reducing the effects of THC and endocannabinoids. This is thought to be the mechanism by which CBD can alter the effects THC, particularly reducing any associated euphoria or \u2018high\u2019.\u00a0<\/span><\/p>\n

 <\/p>\n

In addition to their effects on the endocannabinoid system they have indirect and direct effects on receptors that are involved in pain pathways, mood and anxiety levels, inflammation, and movement<\/strong>.\u00a0<\/span>[\/split_line_heading][\/vc_column_inner][\/vc_row_inner][\/vc_column][vc_column column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”20px” column_link_target=”_self” column_position=”default” zindex=”100″ gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”3\/12″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid” column_padding_type=”default” gradient_type=”default”][vc_row_inner column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” top_padding=”25%” bottom_padding=”25%” top_padding_tablet=”0px” bottom_padding_tablet=”10%” top_padding_phone=”0px” bottom_padding_phone=”10%” text_align=”left” row_position=”relative” row_position_tablet=”inherit” row_position_phone=”inherit” left_position_desktop=”-15%” left_position_tablet=”0px” left_position_phone=”0px” overflow=”visible” pointer_events=”all” css=”.vc_custom_1737544427537{background-color: #e8edeb !important;border-radius: 20px !important;}”][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” el_class=”didascalia-container” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid” column_padding_type=”default” gradient_type=”default”][image_with_animation image_url=”3638″ image_size=”full” animation_type=”entrance” animation=”Fade In” animation_easing=”default” animation_movement_type=”transform_y” hover_animation=”none” alignment=”right” border_radius=”none” box_shadow=”none” image_loading=”default” max_width=”150%” max_width_mobile=”100%” margin_top_tablet=”0px” margin_bottom_tablet=”0px” margin_top_phone=”0px” margin_bottom_phone=”0px” custom_sizes_attr=”100%”][vc_column_text text_direction=”default” css=”.vc_custom_1737712164432{background-color: #e8edeb !important;}”]The Endocannabinoid System[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row type=”full_width_background” full_screen_row_position=”middle” column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” bg_color=”#efe9e9″ scene_position=”center” top_padding=”10%” bottom_padding=”20″ top_padding_phone=”20%” text_color=”dark” text_align=”left” row_border_radius=”none” row_border_radius_applies=”bg” overflow=”visible” overlay_strength=”0.3″ gradient_direction=”left_to_right” shape_divider_position=”bottom” bg_image_animation=”none” gradient_type=”default” shape_type=””][vc_column column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” column_position=”default” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][split_line_heading animation_type=”line-reveal-by-space” font_style=”h2″ text_color=”#0a0a0a” line_reveal_by_space_text_effect=”default” content_alignment=”center” mobile_content_alignment=”inherit” link_target=”_self” text_content=”What is the Endocannabinoid System (ECS)” text_direction=”default”][\/split_line_heading][\/vc_column][\/vc_row][vc_row type=”full_width_background” full_screen_row_position=”middle” column_margin=”default” equal_height=”yes” content_placement=”middle” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” bg_color=”#efe9e9″ scene_position=”center” bottom_padding=”10%” bottom_padding_phone=”20%” text_color=”dark” text_align=”left” row_border_radius=”none” row_border_radius_applies=”bg” overflow=”visible” overlay_strength=”0.3″ gradient_direction=”left_to_right” shape_divider_position=”bottom” bg_image_animation=”none” gradient_type=”default” shape_type=””][vc_column column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” column_position=”default” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/2″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][image_with_animation image_url=”2793″ image_size=”large” animation_type=”entrance” animation=”Grow In” animation_easing=”default” animation_movement_type=”transform_y” hover_animation=”none” constrain_group_5=”yes” alignment=”center” border_radius=”none” box_shadow=”none” image_loading=”default” max_width=”100%” max_width_mobile=”default” margin_top_phone=”60px” margin_bottom_phone=”60px”][vc_column_text text_direction=”default”][\/vc_column_text][\/vc_column][vc_column column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” column_position=”default” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/2″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][tabbed_section style=”material” tab_change_animation=”fade” alignment=”center” spacing=”default” tab_color=”extra-color-gradient-1″ vs_content_animation=”fade” vs_link_animation=”opacity” vs_navigation_alignment=”left” vs_navigation_width_2=”25%” vs_navigation_func=”default” vs_navigation_width=”regular” vs_navigation_spacing=”15px” vs_navigation_mobile_display=”visible” vs_tab_spacing=”5%” icon_size=”24″][tab icon_family=”none” title=”Fig. 01:<\/strong> Central Nervous System” id=”1737712156289-3″ tab_id=”1737712156289-0″][vc_row_inner column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” text_align=”left” row_position=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” pointer_events=”all”][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” centered_text=”true” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid” column_padding_type=”default” gradient_type=”default”][vc_column_text text_direction=”default”]Facilitates the generation of new neurons<\/strong> and is involved in neuroprotection, regulation of motor activity, synaptic plasticity and control of certain memory processing.<\/span>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/tab][tab icon_family=”none” title=”Fig. 02:<\/strong> Gastrointestinal System” id=”1737712156312-8″ tab_id=”1737712156312-8″][vc_row_inner column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” text_align=”left” row_position=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” pointer_events=”all”][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” centered_text=”true” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid” column_padding_type=”default” gradient_type=”default”][vc_column_text text_direction=”default”]\n

Helps protect Gl tract<\/strong> from inflammation and abnormally high gastric and enteric secretions.<\/span><\/p>\n[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/tab][tab icon_family=”none” title=”Fig. 03:<\/strong> Hormones” id=”1737712156329-8″ tab_id=”1737712156329-2″][vc_row_inner column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” text_align=”left” row_position=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” pointer_events=”all”][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” centered_text=”true” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid” column_padding_type=”default” gradient_type=”default”][vc_column_text text_direction=”default”]\n

Plays a significant role in the hypothalamic function which regulates metabolism, reproduction and responses to stress<\/strong>.<\/span><\/p>\n[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/tab][tab icon_family=”none” title=”Fig. 04:<\/strong> Bones” id=”1737712156340-9″ tab_id=”1737712156341-1″][vc_row_inner column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” text_align=”left” row_position=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” pointer_events=”all”][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” centered_text=”true” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid” column_padding_type=”default” gradient_type=”default”][vc_column_text text_direction=”default”]\n

Plays an important role in regulating bone mass<\/strong> and bone regrowth<\/strong>.<\/span><\/p>\n[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/tab][tab icon_family=”none” title=”Fig. 05:<\/strong> Immune System” id=”1737712156358-4″ tab_id=”1737712156358-6″][vc_row_inner column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” text_align=”left” row_position=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” pointer_events=”all”][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” centered_text=”true” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid” column_padding_type=”default” gradient_type=”default”][vc_column_text text_direction=”default”]Regulates the immune system<\/strong> by suppressing proinflammatory cytokine production.<\/span>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/tab][tab icon_family=”none” title=”Fig. 06:<\/strong> Metabolism” id=”1737712156376-4″ tab_id=”1737712156377-3″][vc_row_inner column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” text_align=”left” row_position=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” pointer_events=”all”][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” centered_text=”true” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid” column_padding_type=”default” gradient_type=”default”][vc_column_text text_direction=”default”]\n

Maintains balance<\/strong> by controlling food intake and metabolic functions<\/strong> such as energy storage, nutrient transport and modulating insulin sensitivity.<\/span><\/p>\n[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/tab][tab icon_family=”none” title=”Fig. 07:<\/strong> Muscles” id=”1737712156395-8″ tab_id=”1737712156395-3″][vc_row_inner column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” text_align=”left” row_position=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” pointer_events=”all”][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” centered_text=”true” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid” column_padding_type=”default” gradient_type=”default”][vc_column_text text_direction=”default”]Enhances stamina<\/strong> by regulating blood sugar and encourages ‘runner’s high’.\u00a0 <\/span>Cannabinoid Receptors (CBr)\u00a0<\/span><\/p>\n

Cannabinoid receptors CBr, endocannabinoid, and enzymes form <\/span>the endocannabinoid system (ECS).\u00a0<\/span><\/p>\n

The ECS is our body’s primary regulatory system<\/strong> and is spread out throughout the human body on nearly every organ. It helps regulate vital body functions<\/strong>, including: s<\/span>leep, m<\/span>emory, m<\/span>ood, a<\/span>ppetite, p<\/span>ain, r<\/span>eproduction, i<\/span>nflammation.<\/span>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/tab][tab icon_family=”none” title=”CB-1<\/strong> Receptors” id=”1737712156405-2″ tab_id=”1737712156405-10″][vc_row_inner column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” text_align=”left” row_position=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” pointer_events=”all”][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” centered_text=”true” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid” column_padding_type=”default” gradient_type=”default”][vc_column_text text_direction=”default”]\n

CB-1 is the most abundant in the nervous system<\/strong> (brain and spinal cord). You can also find GB-1 in vital and reproductive organs<\/strong>, connective tissues<\/strong>, various glands<\/strong>, gastrointestinal and urinary tract<\/strong>, and white blood cells<\/strong>.<\/span><\/p>\n

Many tissues contain both CB-1 and CB-2.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/tab][tab icon_family=”none” title=”CB-2<\/strong> Receptors” id=”1737712156425-2″ tab_id=”1737712156425-0″][vc_row_inner column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” text_align=”left” row_position=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” pointer_events=”all”][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” centered_text=”true” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid” column_padding_type=”default” gradient_type=”default”][vc_column_text text_direction=”default”]CB-2 is found predominantly in the immune system<\/strong>. You can also find CB-2 in the gastrointestinal tract<\/strong>, tonsils<\/strong>, and thymus gland<\/strong>.<\/span><\/p>\n

Many tissues contain both CB-1 and CB-2.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/tab][\/tabbed_section][\/vc_column][\/vc_row][vc_row type=”full_width_background” full_screen_row_position=”middle” column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” scene_position=”center” top_padding=”10%” constrain_group_1=”yes” bottom_padding=”10%” top_padding_phone=”20%” constrain_group_5=”yes” bottom_padding_phone=”20%” text_color=”dark” text_align=”left” row_border_radius=”none” row_border_radius_applies=”bg” overflow=”visible” overlay_strength=”0.3″ gradient_direction=”left_to_right” shape_divider_position=”bottom” bg_image_animation=”none” gradient_type=”default” shape_type=””][vc_column column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” sticky_content=”true” sticky_content_functionality=”js” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” column_position=”default” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid” column_padding_type=”default” gradient_type=”default”][tabbed_section style=”vertical_modern” tab_color=”Accent-Color” vs_content_animation=”fade” vs_link_animation=”opacity” vs_navigation_alignment=”left” vs_navigation_width_2=”25%” vs_navigation_func=”default” vs_navigation_width=”regular” vs_navigation_spacing=”15px” vs_navigation_mobile_display=”visible” vs_tab_spacing=”5%”][tab icon_family=”none” title=”ECS” id=”1737712156472-7″ tab_id=”1737712156473-0″][vc_row_inner column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” text_align=”left” row_position=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” pointer_events=”all” el_id=”ecs”][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][vc_column_text text_direction=”default”]\n

The Endocannabinoid System (ECS)<\/h3>\n[\/vc_column_text][vc_column_text text_direction=”default”]The endocannabinoid system (ECS) is a neuro-modulatory system<\/strong> expressed throughout the human central nervous system and the immune system. The ECS consists of neurotransmitters<\/strong> (known as endocannabinoids), receptors<\/strong>, and enzymes<\/strong>. Both endocannabinoids as well as cannabinoids derived from cannabis (phytocannabinoids) are able to interact with these receptors (CB1 and CB2). The endocannabinoid system has been found to play a role in a number physiological and cognitive functions including the regulation of mood<\/strong>, memory<\/strong>, appetite<\/strong>, temperature<\/strong>, and hormone levels<\/strong> as well pain signalling and inflammation<\/strong>.<\/span>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/tab][tab icon_family=”none” title=”Conditions” id=”1737712156494-1″ tab_id=”1737712156495-5″][vc_row_inner column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” text_align=”left” row_position=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” pointer_events=”all” el_id=”conditions”][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][vc_column_text text_direction=”default”]\n

Medical Cannabis May be Prescribed in a Number of Conditions<\/h3>\n[\/vc_column_text][vc_column_text text_direction=”default”]Medical cannabis products can currently be considered for use for a number of indications<\/strong> and can be prescribed by a specialist clinician, supported by a multi-disciplinary team, for diagnosed conditions where first-line therapies have failed. GPs can only prescribe medical cannabis under a shared care agreement with a specialist doctor. GPs can refuse to prescribe medical cannabis products if they believe that they do not have the necessary knowledge to do so.<\/span>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner column_margin=”40px” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” top_padding=”80″ bottom_padding=”50″ left_padding_desktop=”50″ constrain_group_2=”yes” right_padding_desktop=”50″ text_align=”left” row_position=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” pointer_events=”all” class=”first-conditions” css=”.vc_custom_1733303372016{background-color: #e8edeb !important;border-radius: 10px !important;}”][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” centered_text=”true” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/3″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid” column_padding_type=”default” gradient_type=”default”][split_line_heading animation_type=”line-reveal-by-space” font_style=”h3″ text_color=”#084c5f” line_reveal_by_space_text_effect=”default” content_alignment=”default” mobile_content_alignment=”inherit” link_target=”_self” text_content=”Pain conditions” text_direction=”default”][\/split_line_heading][vc_column_text text_direction=”default”]Chronic pain
\n<\/span>Fibromyalgia
\n<\/span>Migraine
\n<\/span>Cluster Headache
\n<\/span>Neuropathic pain
\n<\/span>Cancer-Related Pain
\n<\/span>Ehlers Danlos Syndromes
\n<\/span>Palliative Care\u00a0<\/span>[\/vc_column_text][\/vc_column_inner][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” centered_text=”true” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/3″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid” column_padding_type=”default” gradient_type=”default”][split_line_heading animation_type=”line-reveal-by-space” font_style=”h3″ text_color=”#084c5f” line_reveal_by_space_text_effect=”default” content_alignment=”default” mobile_content_alignment=”inherit” link_target=”_self” text_content=”Psychiatric Conditions” text_direction=”default”][\/split_line_heading][vc_column_text text_direction=”default”]ADHD
\n<\/span>Anxiety
\n<\/span>Agoraphobia
\n<\/span>Autistic Spectrum Disorder
\n<\/span>Depression
\n<\/span>Insomnia
\n<\/span>OCD
\n<\/span>PTSD
\n<\/span>Tourette\u2019s Syndrome<\/span>[\/vc_column_text][\/vc_column_inner][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” centered_text=”true” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/3″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid” column_padding_type=”default” gradient_type=”default”][split_line_heading animation_type=”line-reveal-by-space” font_style=”h3″ text_color=”#084c5f” line_reveal_by_space_text_effect=”default” content_alignment=”default” mobile_content_alignment=”inherit” link_target=”_self” text_content=”Neurological Conditions” text_direction=”default”][\/split_line_heading][vc_column_text text_direction=”default”]Autistic Spectrum Disorder
\n<\/span>Epilepsy
\n<\/span>Migraine
\n<\/span>Cluster headache
\n<\/span>Multiple Sclerosis
\n<\/span>Neuropathic pain
\n<\/span>Parkinson\u2019s Disease\u00a0<\/span>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner column_margin=”40px” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” top_padding=”50″ bottom_padding=”80″ left_padding_desktop=”50″ constrain_group_2=”yes” right_padding_desktop=”50″ text_align=”left” row_position=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” pointer_events=”all” class=”second-conditions” css=”.vc_custom_1733303385876{background-color: #e8edeb !important;border-radius: 10px !important;}”][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” centered_text=”true” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/6″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid” column_padding_type=”default” gradient_type=”default”][\/vc_column_inner][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” centered_text=”true” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”2\/6″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid” column_padding_type=”default” gradient_type=”default”][split_line_heading animation_type=”line-reveal-by-space” font_style=”h3″ text_color=”#084c5f” line_reveal_by_space_text_effect=”default” content_alignment=”default” mobile_content_alignment=”inherit” link_target=”_self” text_content=”Gastrointestinal” text_direction=”default”][\/split_line_heading][vc_column_text text_direction=”default”]Crohn\u2019s Disease
\nUlcerative Colitis
\nIrritable Bowel Syndrome (IBS)
\n[\/vc_column_text][\/vc_column_inner][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” centered_text=”true” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”2\/6″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid” column_padding_type=”default” gradient_type=”default”][split_line_heading animation_type=”line-reveal-by-space” font_style=”h3″ text_color=”#084c5f” line_reveal_by_space_text_effect=”default” content_alignment=”default” mobile_content_alignment=”inherit” link_target=”_self” text_content=”Cancer Related Conditions” text_direction=”default”][\/split_line_heading][vc_column_text text_direction=”default”]Anxiety
\n<\/span>Nausea and Vomiting
\n<\/span>Appetite Loss
\n<\/span>Depression
\n<\/span>Palliative Care\u00a0<\/span>[\/vc_column_text][\/vc_column_inner][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/6″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][\/vc_column_inner][\/vc_row_inner][\/tab][tab icon_family=”none” title=”Contraindications” id=”1737712156622-9″ tab_id=”1737712156622-2″][vc_row_inner column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” text_align=”left” row_position=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” pointer_events=”all” el_id=”contraindications”][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][vc_column_text text_direction=”default”]\n

Contraindications<\/h3>\n[\/vc_column_text][vc_column_text text_direction=”default”]Medical cannabis products are currently not recommended for use in patients who are\/have:\u00a0<\/span><\/p>\n

Pregnancy\/breast feeding<\/strong><\/p>\n

    \n
  • Ongoing or active psychosis\u00a0<\/span><\/li>\n
  • Unstable cardiovascular disease\u00a0<\/span><\/li>\n
  • Allergic reactions to ingredients or excipients\u00a0<\/span><\/li>\n<\/ul>\n

    Caution
    \n<\/strong>When prescribing medical cannabis, health professionals should be cautious of:\u00a0<\/span><\/p>\n

      \n
    • Children\/adolescents<\/span><\/li>\n
    • Interacting medicines\u00a0<\/span><\/li>\n<\/ul>\n[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/tab][tab icon_family=”none” title=”Evidence” id=”1737712156645-9″ tab_id=”1737712156645-1″][vc_row_inner column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” text_align=”left” row_position=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” pointer_events=”all” el_id=”evindence”][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][vc_column_text text_direction=”default”]\n

      General Evidence for Medical Cannabis<\/h3>\n[\/vc_column_text][vc_column_text text_direction=”default”]Humans have been using cannabis for a number of indications for thousands of years, however, our scientific understanding of the active compounds within the plant has only developed in recent decades. Due to the interactions between cannabinoids and the human endocannabinoid system, medical cannabis may be prescribed for a large number of indications<\/strong>.\u00a0<\/span><\/p>\n

      According to the UK Medical Cannabis Registry, chronic pain<\/strong> is the most common reason why people are prescribed medical cannabis. After this the next most common are psychiatric <\/strong>and neurological conditions<\/strong>.\u00a0<\/span><\/p>\n

      Clinical research into medical cannabis is still in its infancy so there remains a general lack of high-quality clinical evidence to either support, or oppose, the use of CBMPs. However, there is a large base of real world evidence<\/strong>, such as that collected in databases and registries.\u00a0<\/span>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/tab][tab icon_family=”none” title=”Side Effects” id=”1737712156668-3″ tab_id=”1737712156669-7″][vc_row_inner column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” text_align=”left” row_position=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” pointer_events=”all” el_id=”side-effects”][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][vc_column_text text_direction=”default”]\n

      Common Side Effects<\/h3>\n[\/vc_column_text][vc_column_text text_direction=”default”]The side effects of medical cannabis can vary widely depending on the patient and the products used<\/strong>. The existing evidence suggests that side effects can differ from mild to serious and can include:<\/span>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” top_padding=”50″ constrain_group_1=”yes” bottom_padding=”50″ left_padding_desktop=”50″ constrain_group_2=”yes” right_padding_desktop=”50″ text_align=”left” row_position=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” pointer_events=”all” css=”.vc_custom_1733303644906{background-color: #e8edeb !important;border-radius: 10px !important;}”][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/3″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid” column_padding_type=”default” gradient_type=”default”][split_line_heading animation_type=”line-reveal-by-space” font_style=”h3″ text_color=”#084c5f” line_reveal_by_space_text_effect=”default” content_alignment=”default” mobile_content_alignment=”inherit” link_target=”_self” text_content=”Very common side effects (more than one in 10 people)” text_direction=”default”][\/split_line_heading][vc_column_text text_direction=”default”]\n
        \n
      • feeling drowsy or sleepy\u00a0<\/span><\/li>\n
      • decreased appetite\u00a0<\/span><\/li>\n
      • diarrhoea\u00a0<\/span><\/li>\n
      • fever\u00a0<\/span><\/li>\n
      • feeling tired\u00a0<\/span><\/li>\n
      • vomiting or nausea\u00a0<\/span><\/li>\n<\/ul>\n[\/vc_column_text][\/vc_column_inner][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/3″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid” column_padding_type=”default” gradient_type=”default”][split_line_heading animation_type=”line-reveal-by-space” font_style=”h3″ text_color=”#084c5f” line_reveal_by_space_text_effect=”default” content_alignment=”default” mobile_content_alignment=”inherit” link_target=”_self” text_content=”Common side effects (more than 1 in 100 people)” text_direction=”default”][\/split_line_heading][vc_column_text text_direction=”default”]\n
          \n
        • lack of energy or giddy\u00a0<\/span><\/li>\n
        • blurred vision\u00a0<\/span><\/li>\n
        • eating more than usual\u00a0<\/span><\/li>\n
        • difficulty speaking\u00a0<\/span><\/li>\n
        • change of taste or dry mouth\u00a0<\/span><\/li>\n
        • constipation\/diarrhoea\u00a0<\/span><\/li>\n
        • cold, sore throat\/mouth\u00a0<\/span><\/li>\n
        • respiratory tract infections (pneumonia, bronchitis)\u00a0<\/span><\/li>\n
        • blood tests showing increases in levels of certain liver enzymes or damage to the liver (signs include: abdominal pain, unexplained nausea and malaise, darkening of urine or jaundice)\u00a0<\/span><\/li>\n
        • shaking, of the body or parts of it\u00a0<\/span><\/li>\n
        • feeling bad-tempered (irritable, aggressive)\u00a0<\/span><\/li>\n
        • difficulty sleeping\u00a0<\/span><\/li>\n
        • cough\u00a0<\/span><\/li>\n
        • rash\u00a0<\/span><\/li>\n
        • increased appetite or weight loss\u00a0<\/span><\/li>\n
        • sialorrhea (drooling)\u00a0<\/span><\/li>\n
        • urinary tract infection\u00a0<\/span><\/li>\n
        • abnormal behaviours or agitation\u00a0<\/span><\/li>\n
        • loss of balance or falling over\u00a0<\/span><\/li>\n<\/ul>\n[\/vc_column_text][\/vc_column_inner][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/3″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid” column_padding_type=”default” gradient_type=”default”][split_line_heading animation_type=”line-reveal-by-space” font_style=”h3″ text_color=”#084c5f” line_reveal_by_space_text_effect=”default” content_alignment=”default” mobile_content_alignment=”inherit” link_target=”_self” text_content=”Uncommon (affecting less than 1 in 100 people)” text_direction=”default”][\/split_line_heading][vc_column_text text_direction=”default”]\n
            \n
          • fainting\u00a0<\/span><\/li>\n
          • changes in pulse rate, heart rate or blood pressure\u00a0<\/span><\/li>\n
          • tummy pain\u00a0<\/span><\/li>\n
          • mouth or teeth changing colour\u00a0<\/span><\/li>\n<\/ul>\n[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/tab][\/tabbed_section][\/vc_column][\/vc_row]\n","protected":false},"excerpt":{"rendered":"

            [vc_row type=”full_width_background” full_screen_row_position=”middle” column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” bg_color=”#454156″ bg_image=”238″ bg_position=”center center” background_image_loading=”default” bg_repeat=”no-repeat” scene_position=”center” top_padding=”5%” bottom_padding=”5%” text_color=”light” text_align=”left” row_border_radius=”none” row_border_radius_applies=”bg” overflow=”visible” id=”intro” row_name=”Intro” enable_gradient=”true” color_overlay=”#0a0a0a” color_overlay_2=”rgba(102,102,102,0.74)” overlay_strength=”0.3″ gradient_direction=”left_b_to_right_t” shape_divider_position=”bottom” bg_image_animation=”none”…<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":3365,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-3367","page","type-page","status-publish"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.curaleafeducation.it\/en-uk\/wp-json\/wp\/v2\/pages\/3367","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.curaleafeducation.it\/en-uk\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.curaleafeducation.it\/en-uk\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.curaleafeducation.it\/en-uk\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.curaleafeducation.it\/en-uk\/wp-json\/wp\/v2\/comments?post=3367"}],"version-history":[{"count":15,"href":"https:\/\/www.curaleafeducation.it\/en-uk\/wp-json\/wp\/v2\/pages\/3367\/revisions"}],"predecessor-version":[{"id":4856,"href":"https:\/\/www.curaleafeducation.it\/en-uk\/wp-json\/wp\/v2\/pages\/3367\/revisions\/4856"}],"up":[{"embeddable":true,"href":"https:\/\/www.curaleafeducation.it\/en-uk\/wp-json\/wp\/v2\/pages\/3365"}],"wp:attachment":[{"href":"https:\/\/www.curaleafeducation.it\/en-uk\/wp-json\/wp\/v2\/media?parent=3367"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}